As far as drugs go, ibuprofen seems pretty harmless. Information technology takes the edge off nasty hangovers or headaches and soothes sore muscles, and it's easy to discover on just about every drug store shelf in America. It even comes in single-serving wrappers for moments of urgent demand.
"If used sparingly, [Advil] rarely causes whatsoever major side effects," says Nauman Tariq, M.D., an assistant professor of neurology and the director of the Headache Center at Johns Hopkins Hospital. (Tariq says a safety dosage is usually 600mg a day, or about three tablets a day, once or twice a week.)
But while drugs similar Advil (otherwise known as nonsteroidal anti-inflammatory drugs, or NSAIDs) aren't going to give you compulsive, uncontrollable urges to adventure or rupture a tendon in your leg (yep, some mutual drugs really practise take those side effects), taking a ton of ibuprofen on a long-term basis does come with health risks. "If you want my stance, I would err toward caution and would not recommend frequent use of this drug," Tariq says.
Then what tin can happen if you take a ton of ibuprofen over a long period of time? We asked Tariq and other health experts to outline some of the potential risks.
2 You might accept issues keeping information technology upwardly.
Yup — long-term ibuprofen use can pb to bug maintaining an erection. That's considering Advil and other NSAIDs can result in decreased release of prostaglandin, a family of chemicals that "play an important role in erection," says Tariq. In fact, some erectile dysfunction (ED) patients even become prostaglandin injections from their urologists as function of their treatment.
"Theoretically speaking, Advil has the potential to adversely bear upon erection if taken for a long time," he notes.
But going limp isn't a given. The science regarding sexual wellness and Advil is mixed: another study in BJU International found no relationship between NSAID utilise and ED. And so don't toss all your Advil but nonetheless.
3 Heartburn and stomach woes.
Post-workout musculus fire hurts and then practiced. Post-Advil heartburn? Not then much.
If your stomach hurts after taking the pills, here's what's probable going on: ibuprofen blocks the release of prostaglandin, which protects the tummy against tum acid, explains Tariq. "Frequent [Advil] use can irritate the stomach lining, hence causing heartburn and stomach hurting."
The Advil website explicitly notes this, stating: "This production contains an NSAID, which may cause astringent stomach bleeding." This only relates to long-term, consequent employ, though, so just remember: dose is primal.
It might audio counterintuitive, but if you use ibuprofen more than than three or four times a calendar week to treat headaches, you might create a headache of your ain. Y'all could be at risk for what Tariq calls "medication overuse headaches," a.1000.a.rebound headaches.
Doctors aren't sure why rebound headaches occur, notes Tariq, only they can be common for people who make popping NSAIDs a habit. He says it could exist that chronic exposure to NSAIDs tin can lead to changes in hormones and inhibitory pathways that translate to constant feelings of head pain, just information technology's as well possible that some people are just predisposed to headaches in general.
Some research in both humans and animals suggests that high doses of NSAIDs such equally ibuprofen tin can lead to tinnitus (a ringing in the ears). "In animals, prolonged use has been shown to cause decease of some of the hearing cells," notes Tariq. But it's worth noting this is often a rare side result linked with high usage — and the problem usually fades after you stop taking the drugs.
Because ibuprofen blocks many different pathways in the body, allergic reactions, including rashes, are possible equally a result of overuse, explains Shanna Levine, One thousand.D., an internist at the Mountain Sinai Hospital in New York.
That said, generally speaking, whatever drug has the potential to cause a skin allergic reaction. "They're foreign chemicals introduced in the body, and so the body starts to make antibodies against and this can cause an allergic reaction," explains Tariq.
Feeling puffy? While information technology might sound counterintuitive for an anti-inflammatory to leave you, well, inflamed, prostaglandin likewise works to promote sodium excretion and blood flow to the kidneys, explains Levine. If your torso hangs on to excess sodium instead of excreting it, you could current of air upward looking a lilliputian bloated.
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